Dr. Cornelia MEINERT
Chargé de Recherche (CNRS) specialized in
multidimensional and enantioselective analyses
University Nice Sophia Antipolis, France
Tél
: +33 (0)4 92 07 61 36
Cornelia.Meinert@unice.fr
Research
Interests
Highly interested in separation
science & instrumental methods
Analysis of complex samples: amino acids,
environmental samples
Enantioselective separation of amino acids
using two-dimensional gas chromatography
(GCxGC)
Origin of biomolecular asymmetry
Publications
- Meinert
C., Myrgorodska I.,de Marcellus P., Buhse
T., Nahon
L., Hoffmann
S.V., Le Sergeant d'Hendecourt L.,
Meierhenrich U. J.: Ribose and related
sugars from ultraviolet irradiation of
interstellar ice analogs. Science
352
(2016), 208-212.
- Myrgorodska
I., Meinert
C., Martins
Z., d'Hendecourt L., Meierhenrich U. J.:
Quantitative enantioseparation of amino
acids by comprehensive two-dimensional gas
chromatography applied to non-terrestrial
samples. Journal of
Chromatography A 1433
(2016), 131-136.
- de
Marcellus
P., Meinert C., Myrgorodska I., Nahon L.,
Buhse T., d'Hendecourt L., Meierhenrich U.
J.: Aldehydes and sugars from evolved
precometary ice analogs: importance of ices
in astrochemical and prebiotic evolution. Proc. Natl.
Acad. Sci. USA 112
(2015), 965-970.
- Myrgorodska
I.,
Meinert C., Martins Z., d'Hendecourt L.,
Meierhenrich U. J.: Molecular chirality in
meteorites and interstellar ices, and the
chirality-experiment onboard ESA's cometary
Rosetta mission. Angew. Chem.
Int. Ed. 54 (2015), 1402-1412.
- Meinert
C.,
Cassam-Chenaï P., Jones N.C., Nahon L.,
Hoffmann S.V., Meierhenrich U. J.:
Anisotropy-guided enantiomeric enhancement
in alanine using far-UV circularly polarized
light. Orig. Life
Evol. Biosph. 45
(2015), 149-162.
- Bredehöft
J.H.,
Jones N.C., Meinert C., Hoffmann S. V.,
Evans A.C., Meierhenrich U. J.:
Understanding Photochirogenesis -
Solvent-effects on circular dichroism and
anisotropy spectroscopy. Chirality 26 (2014),
373-378.
- Meinert
C.,
Hoffmann S. V., Cassam-Chenaï P., Evans A.
C., Giri C., Nahon L., Meierhenrich U. J.:
Photonenergy-controlled Symmetry Breaking
with Circularly Polarized Light. Angew. Chem.
Int. Ed. 53 (2014), 210-214.
- Meinert
C.,
Meierhenrich U. J.: Derivatization and
Multidimensional Gas-Chromatographic
Resolution of alpha-Alkyl and alpha-Dialkyl
Amino Acid Enantiomers. ChemPlusChem
79 (2014),
781-785.
- Modica
P.,
Meinert C., de Marcellus P., Nahon L.,
Meierhenrich U.J., d'Hendecourt L.:
Enantiomeric excesses induced in amino acids
by ultraviolet circularly polarized light
irradiation of extraterrestrial ice analogs:
a possible source of asymmetry for prebiotic
chemistry. The Astrophysical Journal
788 (2014),
79.
- Evans
A. C., Meinert C., Bredehöft J. H., Giri C.,
Jones N. C., Hoffmann S. V., Meierhenrich U.
J.: Anisotropy Spectra for Enantiomeric
Differentiation of Biomolecular Building
Blocks. Top.
Curr. Chem. 341 (2013),
271-300.
- Giri
C., Goesmann F., Meinert C., Evans A. C.,
Meierhenrich U. J.: Synthesis and Chirality
of Amino Acids Under Interstellar
Conditions. Top. Curr. Chem. 333 (2013),
41-82.
- Meinert
C.,
Meierhenrich U. J.: A new dimension in
separation science - comprehensive
two-dimensional gas chromatography. Angew. Chem.
Int. Ed. 51 (2012), 10460-10470.
- Evans
A. C., Meinert C., Giri C., Goesmann F.,
Meierhenrich U. J.: Chirality,
photochemistry and the detection of amino
acids in interstellar ice analogues and
comets. Chem.
Soc. Rev. 41
(2012), 5447-5458.
- Meinert
C.,
Bredehöft J. H., Filippi J.-J., Baraud Y.,
Nahon L., Wien F., Jones N. C., Hoffmann S.
V., Meierhenrich U. J.: Anisotropy Spectra
of Amino Acids. Angew. Chem. Int. Ed. 51
(2012), 4484-4487.
- Meinert
C.,
Filippi J.-J., de Marcellus P., le Sergeant
d'Hendecourt L., Meierhenrich U. J.: N-(2-Aminoethyl)glycine
and
Amino Acids in Interstellar Ice Analogues. ChemPlusChem
77 (2012), 186-191.
- Meierhenrich
U.
J., Filippi J.-J., Meinert C., Hoffmann S.
V., Bredehöft J. H., Nahon L.: Photolysis of
rac-Leucine
with
Circularly Polarized Synchrotron Radiation.
In: D-Amino
Acids in Chemistry, Life Sciences, and
Biotechnology. Eds. Brückner H.,
Fujii N., Wiley-VCH, Weinheim (2011),
341-349.
- Meinert
C.,
de Marcellus P., Le Sergeant d'Hendecourt
L., Nahon L., Jones N. J., Hoffmann S. V.,
Bredehöft J. H., Meierhenrich U. J.:
Photochirogenesis: Photochemical Models on
the Absolute Asymmetric Formation of Amino
Acids in Interstellar Space. Physics of
Life Reviews 8 (2011),
307-330
Physics of
Life Reviews 8 (2011),
337-338.
- De
Marcellus
P., Meinert C., Nuevo M., Filippi J.-J.,
Danger G., Deboffle D., Nahon L., Le
Sergeant d'Hendecourt L., Meierhenrich U.
J.: Non-Racemic Amino Acids Production by
Ultraviolet Irradiation of Achiral
Interstellar Ice Analogs with Circularly
Polarized Light. The Astrophysical Journal Letters
727 (2011), L27.
- Meierhenrich
U.
J., Filippi J.-J., Meinert C., Bredehöft J.
H., Takahashi J., Nahon L., Jones N. C.,
Hoffmann S. V.: Circular Dichroism of Amino
Acids in the Vacuum-Ultraviolet Region. Angew. Chem.
Int. Ed. 49 (2010),
7799-7802.
- Meierhenrich
U.
J., Filippi J.-J., Meinert C., Vierling
P.,
Dworkin J. P.: On the Origin of Primitive
Cells - From Nutrient Intake to Elongation
of Encapsulated Nucleotides. Angew. Chem.
Int. Ed. 49 (2010),
3738-3750.
- Meierhenrich
U.
J., Filippi J.-J., Meinert C., Hoffmann S.
V., Bredehöft J. H., Nahon L.: Photolysis
of
rac-Leucine
with Circularly Polarized Synchrotron
Radiation. Chemistry & Biodiversity 7
(2010), 1651-1659.
- Meinert
C.,
Filippi
J.-J.,
Hoffmann
S.
V., Le
Sergeant
d'Hendecourt L., de
Marcellus
P., Bredehöft
J.
H., Thiemann W. H.-P., Meierhenrich U. J.:
Photochirogenesis: Photochemical Models on
the Origin of Biomolecular Homochirality. Symmetry 2
(2010), 1055-1080.
- Meinert
C.,
Schymanski E., Kuester E., Schüürmann G.,
Brack W.: Application of preparative
capillary gas chromatography (pcGC),
automated structure generation and
mutagenicity prediction to improve
effect-directed analysis of genotoxicants in
a contaminated groundwater. Environmental
Science & Pollution Research 17
(2009), 885-897.
- Meinert C., Brack W.:
Optimisation of injection, separating and
trapping parameters in preparative capillary
gas chromatography. Chemosphere 78
(2009), 416-422.
- Schymanski, Meinert et al. 2008. The use
of MS classifiers and structure generation
to assist in the identification of unknowns
in effect-directed analysis. Anal.Chim.Acta
615 (2), 136-147.
- Meinert et al. 2007. Fractionation of technical p-nonylphenol with
preparative capillary gas chromatography. Chemosphere 70 (2), 215-223.
Conferences
- Meierhenrich U.J., Meinert C.,
Myrgorodska I., de Marcellus P., Buhse T., Nahon L., Hoffmann
S.V., d'Hendecourt L.: Organic molecules detected in
cometary ice analogs and in comet 67P by the
Rosetta Philae Lander. Chirality 2016
Symposium, University of Heidelberg, 24-27
July 2016, Germany.
- Myrgorodska I., Meinert C., de Marcellus P., d'Hendecourt L., Hoffmann S.V., Nahon L.,
Meierhenrich U.J.: Asymmetric
photolysis of chiral molecules of prebiotic
importance at synchrotron SOLEIL. Colloquium
at the Japan Agency for Marine-Earth Science
and Technology JAMSTEC, Yokosuka, Kanagawa,
Japan, 9 March 2016.
- Le Sergeant d'Hendecourt L., de
Marcellus P., Meinert C., Myrgorodska I.,
Modica P., Nahon L., Buhse T., Meierhenrich
U.J.: Why interstellar ices can be
considered as precursors for prebiotic
chemistry? IAU XXIX General Assembly,
Honolulu, Hawaii, U.S.A., 3-14 August 2015.
- Meinert C., Meierhenrich U.J.
et al.: Chiral Photons as Trigger of Life's
Handedness? Astrobiology Science Conference
(AbSciCon), Chicago, U.S.A., 15-19 June
2015.
- Nahon L., Tia M., Garcia G.,
Cunha de Miranda B., Meinert C.,
Meierhenrich U.J., Myrgorodska I., de
Marcellus P., Modica P., Le Sergeant
d'Hendecourt L.: Astrophysical scenarii for
the origin of biomolecular asymmetry probed
by circularly-polarized VUV synchrotron
radiation. Astrobiology Science Conference
(AbSciCon), Chicago, U.S.A., 15-19 June
2015.
- Le Sergeant d'Hendecourt L., de
Marcellus P., Meinert C., Myrgorodska I.,
Modica P., Nahon L., Buhse T., Meierhenrich
U.J.: The importance of extraterrestrial
ices in astrochemical and prebiotic
evolution. Astrobiology Science Conference
(AbSciCon), Chicago, U.S.A., 15-19 June
2015.
- Meinert C., Hoffmann S.V., Nahon L.,
d'Hendecourt L., Meierhenrich U.J.: Chiral
Photons as Trigger of Life's Asymmetry?
PTPC2014 - Photon Tools for Physical
Chemistry, Beatenberg, Switzerland 28
September - 1 October 2014.
- Hoffmann S.V., Jones N.C.,
Meinert C., Bredehöft J.H., Nahon L.,
Meierhenrich U.J.: Anisotropy spectroscopy
on chiral organic molecules. Chirality 2014,
Prague, Czech Republic, 27-30 July 2014.
- Meinert C., Hoffmann S.V., Nahon L.,
Myrgorodska I., d'Hendecourt L., Meierhenrich U.J.: Chiral
Photons as Trigger of Life's Asymmetry. The
International Astrobiology Society and
Bioastronomy (IAU C51) Joint International
Conference, Nara, Japan 6-11 July 2014.
- Myrgorodska I., Meinert C., Martins Z., d'Hendecourt L.,
Meierhenrich U.J.: Multidimensional Analysis
of Amino Acids in Murchison Meteorite. The International Astrobiology
Society and Bioastronomy (IAU C51) Joint
International Conference, Nara, Japan 6-11
July 2014.
- Meierhenrich U.J., Evans A.,
Meinert C., Hoffmann S.V., Nahon L.: The
Asymmetry of Life in the Light of Chiral
Photons. 3rd European GCxGC Symposium, Nice,
France, 17-18 September 2013.
- Nahon L., Tia M., Garcia G.,
Meinert C., Meierhenrich U.J., de Marcellus
P., Modica P., Le Sergeant d'Hendecourt L.:
Asymmetric photon-induced processes on
chiral species with circularly-polarized
synchrotron radiation: a possible
astrophysical scenario for the origin of
biomolecular asymmetry. First Workshop on
Experimental Laboratory Astrophysics, Poipu,
Kauai, Hawaii, U.S.A., 25-27 February 2013.
- Meierhenrich U.J., Evans A.,
Meinert C., Hoffmann S.V.: Anisotropy
Spectroscopy of Biomolecules. 8th SOLEIL
Users' Meeting, Synchrotron SOLEIL,
Gif-sur-Yvette, France 23-24 January 2013.
- Modica P., Meinert C., de
Marcellus P., Nahon L., Meierhenrich U.J.,
Le Sergeant d'Hendecourt L.: Amino acid
enantiomeric excesses induced by VUV
circularly polarized light in interstellar
ice analogs. COST Annual Meeting, The
Chemical Cosmos, Catania, Italy, 2-5 October
2012.
- Evans A., Meinert C., Hoffmann
S. V., d'Hendecourt L., Nahon L., Goesmann
F., Giri C., Meierhenrich U. J.:
Photochemical synthesis, chirality and
detection of amino acids in interstellar ice
analogues and comets. 21st IUPAC
International Conference on Physical Organic
Chemistry, ICPOC21, Durham University, UK,
9-13 September 2012.
- Evans A., Meinert C., Hoffmann
S. V., d'Hendecourt L., Nahon L., Goesmann
F., Giri C., Meierhenrich U. J.:
Photochemical synthesis, chirality and
detection of amino acids in interstellar ice
analogues and comets. AbGradCon, California
Institute of Technology, Pasadena, United
States 27-30 August 2012.
- Giri C., Meinert C., Hoffmann
S. V., Evans A., d'Hendecourt L., Nahon L.,
Goesmann F., Meierhenrich U. J.: Formation
and chiroptical properties of amino acids in
interstellar ice analogues. 39th Scientific
Assembly of the Committee on Space Research
COSPAR, Mysore, India, 14-22 July 2012.
- Giri C., Meinert C., Evans A.,
Goesmann F., Meierhenrich U. J.: The sojourn
of chiral organics from ISM to comets - the
COSAC experiment onboard Rosetta. AstroChem
Conference, Kolkata, India, 10-13 July 2012.
- Evans A., Meinert C., Hoffmann
S. V., d'Hendecourt L., Nahon L., Goesmann
F., Giri C., Meierhenrich U. J.:
Photochemical synthesis, chirality and
detection of amino acids in interstellar ice
analogues and comets. Astrobiology Science
Conference, AbSciCon, Atlanta, United States
16-20 April 2012.
- Meinert C., Meierhenrich U. J.:
The origin of biomolecular asymmetry -
insights from cometary matter using
multidimensional gas chromatography. 2nd
European GCxGC Symposium, Universität
Regensburg, Germany, 20-21 September
2011.
- Meinert C., Meierhenrich U. J.:
The origin of life - enantioselective
analysis of amino acids in interstellar ice
analogues and meteorites by multidimensional
GC-MS. LECO conference on GCxGC. University
of Aachen, Germany, 30 November - 1 December
2010.
Professional
experience
(2004-2009) PhD Student,
Helmholtz Centre for Environmental Research,
Leipzig
(2003-2004) Diploma thesis,
Helmholtz Centre for Environmental Research
Leipzig
(2002-2003) Student Research
Assistant, Leipniz Instiute for Tropospheric
Research, Leipzig
(2002-2004) Master of Chemistry,
University of Leipzig, Germany
(1999-2002) Bachelor of
Chemistry, University of Rostock, Germany
Memberships
Gesellschaft Deutscher Chemiker
(GDCh)
Society of Environmental
Toxicology and Chemistry (SETAC)
My favourite
motto :)
Shoot for the moon: Even if you miss
you'll still be among the stars!
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