Institut de Chimie de Nice UMR 7272

Professor

• APSM Team
• Group leader "Synthesis & Catalytic Methodologies"
• Tel : +33 (0)4 92 07 61 31
• E-mail : veronique.michelet@unice.fr

Research topics

 Formation of C-C, C-O, C-N & C-F bonds via catalysis (Pd, Cu, In, Ni, Rh, Pt, Ir, Ag et Au…)
 Atom-economical processes
 Asymmetric Catalysis
 Metallo-organocatalysis & organocatalysis
 Catalysis in water
 Synthesis and applications of novel atropoisomeric and/or hydrosoluble ligand
 Novel fluorescent molecules : synthesis et photophysical properties, complexation of pollutant cations

Professional background

 Since 2017 Professor - University of Nice Sophia- Antipolis
 Since 2007 CNRS Research Director - ENSCP - Chimie ParisTech -
 1998-2006 CNRS Associate Researcher - ENSCP - Chimie ParisTech -
 1998 Post-doctoral internship, Imperial College (London, GB), Laboratory of Pr. A. G. M. Barrett, “Synthesis of polypeptides over solid support. Application to biopolymeres recognition”
 1997 Post-doctoral internship, University of Pennsylvania (Philadelphia, USA), Laboratory of Pr. J. D. Winkler, “Synthesis of photosensible macrocycle. Applications to the photodynamic detection and transportation of metallic ions”
 1993-1996 PhD of Organic Chemistry, University Pierre & Marie Curie (Paris 6). “ Synthetic Approach of the west part of ambruticin and analogues via Pd-catalyzed alkylation and cyclopropanation strategies.” under the supervision of Pr. J.-P. Genêt

Book

“Gold Catalysis : An Homogeneous Approach” Edited by F. Dean Toste & Véronique Michelet Imperial College Press, Catalytic Science Series : Volume 13, 2014.

Selection of recent publications

 Ye, F. ; Haddad, M. ; Ratovelomanana-Vidal, V. ; Michelet, V. Org. Lett. 2017, 19, 1104-1107. “Ruthenium-Catalyzed [2+2+2] Cycloaddition Reaction Forming 2-Aminopyridine Derivatives from α,ω-Diynes and Cyanamides”

 Arcadi, A. ; Chiarini, M. ; Del Vecchio, L. ; Marinelli, F. ; Michelet, V. Eur. J. Org. Chem. 2017, 2214-2222. “Sequential Silver-Catalyzed Oxidative Cyclization Reactions of Unprotected 2-Alkynylanilines to Anthranils”. VIP article, Cover picture.

 Tomas-Mendivil, E. ; Heinrich, C. ; Ortuno, J.-C. ; Starck, J. ; Michelet, V. ACS Catal. 2017, 7, 380-387. “Gold-catalyzed access to 1H-isochromenes : reaction development and mechanistic insight”

 Ye, F. ; Haddad, M. ; Michelet, V. ; Ratovelomanana-Vidal, V. Org. Lett. 2016, 18, 5612-5615. “Access toward Fluorenone Derivatives through Solvent-Free Ruthenium Trichloride Mediated [2 + 2 + 2] Cycloadditions”

 Le Boucher d’Herouville, F. ; Millet, A. ; Scalone, M. ; Michelet, V. Synthesis 2016, 48, 3309-3316. "Synthesis of Atropisomeric MeOBIPHEP Analogues and Their Application in Silver-Catalyzed Cycloisomerization of Allenols"

 Carrër, A. ; Péan, C. ; Perron-Sierra, F. ; Mirguet, O. ; Michelet, V. Adv. Synth. Catal. 2016, 358, 1540-1545. "Gold-Catalyzed Cyclizations of Alkynyl Silyl Enol Ethers : an Easy Access to Bicyclo[3.2.1]octanone Derivatives”

 Laugeois, M. ; Ponra, S. ; Ratovelomanana-Vidal, V. ; Michelet, V. ; Vitale, M.R. Chem. Commun. 2016, 52, 5332-5335. “Asymmetric preparation of polysubstituted cyclopentanes by synergistic Pd(0)/amine catalyzed formal [3+2] cycloadditions of vinyl cyclopropanes with enals”

 Arcadi, A. ; Chiarini, M. ; Del Vecchio, L. ; Marinelli, F. ; Michelet, V. Chem. Commun. 2016, 52, 1458-1461. “Silver- versus gold-catalyzed sequential oxidative cyclization of unprotected 2-alkynylanilines with oxone“

 Tomas-Mendivil, E. ; Starck, J. ; Ortuno, J.-C. ; Michelet, V. Org. Lett. 2015, 17, 6126-6129. “Synthesis of Functionalized 1H-Isochromene Derivatives via a Au-Catalyzed Domino Cycloisomerization/Reduction Approach”. Selected for Organic Chemistry Portal www.organic-chemistry.org/ab..., www.organic-chemistry.org/ch... and http://www.organic-chemistry.org/sy...

 Moragues, A. ; Neatu, F. ; Pârvulescu, V.I. ; Marcos, M. D. ; Amorós, P. ; Michelet, V. ACS Catal. 2015, 5, 5060-5067. “Heterogeneous gold catalyst : synthesis, characterization and application in 1,4-addition of boronic acids to enones”